Protein Info for Atu4758 in Agrobacterium fabrum C58
Annotation: ectoine utilization protein EutC
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 70% identical to Y0419_RHIME: Putative dehydrogenase RB0419 (eutC) from Rhizobium meliloti (strain 1021)
KEGG orthology group: K01750, ornithine cyclodeaminase [EC: 4.3.1.12] (inferred from 100% identity to atu:Atu4758)Predicted SEED Role
"Ornithine cyclodeaminase (EC 4.3.1.12)" in subsystem Arginine and Ornithine Degradation (EC 4.3.1.12)
MetaCyc Pathways
- L-arginine degradation VII (arginase 3 pathway) (2/2 steps found)
- L-ornithine degradation I (L-proline biosynthesis) (1/1 steps found)
- L-proline biosynthesis II (from arginine) (1/2 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 4.3.1.12
Use Curated BLAST to search for 4.3.1.12
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A9CH35 at UniProt or InterPro
Protein Sequence (337 amino acids)
>Atu4758 ectoine utilization protein EutC (Agrobacterium fabrum C58) MSQINILTEKDLRAVVKLDLSAIDCVERAFSALATEAVAMPPILRLDIPEFRGEVDVKTA YVPGFDGFAIKVSPGFFDNPKLGLPSLNGLMILFSARTGLVDAMLLDNGYLTDVRTAAAG AVAARHLAREDASVAAIFGAGMQARLQLEALTLARPIRSARIWARNHDRAEKLASDFARE HGIDVIAMTDPRAALQGADIIVTTTPAETPILLADWLEEGQHLTAMGSDAEHKNEIDPAV FAKARYVADRLSQTRILGELHHAIAAGRVAPDQPFPELGAIIAGKAQGRRSNDDITFADL TGTGVQDTAIANLAFTRAKDAGSGQIIENTVKMGDAA