Protein Info for Atu4600 in Agrobacterium fabrum C58

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 587 transmembrane" amino acids 26 to 50 (25 residues), see Phobius details amino acids 65 to 90 (26 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 256 to 276 (21 residues), see Phobius details amino acids 282 to 299 (18 residues), see Phobius details PF00664: ABC_membrane" amino acids 32 to 293 (262 residues), 127.3 bits, see alignment E=9.5e-41 PF00005: ABC_tran" amino acids 362 to 511 (150 residues), 118.9 bits, see alignment E=2.7e-38

Best Hits

Swiss-Prot: 60% identical to Y4GM_SINFN: Uncharacterized ABC transporter ATP-binding protein y4gM (NGR_a03510) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 100% identity to atu:Atu4600)

MetaCyc: 40% identical to lipid A-core oligosaccharide flippase (Brucella abortus 2308)
RXN2B4Q-67 [EC: 7.5.2.6]

Predicted SEED Role

No annotation

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGV8 at UniProt or InterPro

Protein Sequence (587 amino acids)

>Atu4600 ABC transporter permease (Agrobacterium fabrum C58)
MIGSFLSPDDKKLLTRLFKENFKKHVGWYSAAIVAMLLVAGTTSLSAWIMRDIVNSVYLK
QGFDVVLEIAFAVAAIFIVKGLATFVQSYYLSKAGNSIVAEQQRKIYDRLLKQGVSFFQN
LPSSELLVRVTYNAQAARSVIDTIVTSFVRDLFSLLGLIIVMFAQNFLLSAISMIIGPVA
IFSVRLVLRRVRKIMEAELASLGEIVNVVQETSIGVRVIKAFSLEKLMRQRMNKAVSDVE
HRANGIAKLEAATSPIMETLSGLAIAVVIAVSGYTVLEKGGSPGDLMAFITALLLAYEPA
KRLARMRVQIEGGMIGVRMMFEVLDAPLTLAEKKDAQPLPKASGNVELKNVSFEYVANQP
VLKDVSVLFEGGKMTALVGPSGSGKSTIINLMMRLYDPQSGSVEINGMDLRDVSFASLRE
HVSYVGQETFLFSGTVKHNISVGRDNATDEEIIAAAKAANAHDFIMNMPDGYDSKLGENG
SGLSGGQRQRVAIARAMLRDADILILDEATSALDSESEALVRDALERLTLNKTSIVIAHR
LSTINRADKIVVMDNGQVVEQGSRRELLATDGLYKRLHSIQFDADVA