Protein Info for Atu4598 in Agrobacterium fabrum C58

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 PF00005: ABC_tran" amino acids 34 to 173 (140 residues), 107 bits, see alignment E=1.2e-34

Best Hits

Swiss-Prot: 50% identical to Y4187_BRUSU: Putative ATP-binding protein BRA1187/BS1330_II1178 (BRA1187) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 100% identity to atu:Atu4598)

Predicted SEED Role

"Hydroxymethylpyrimidine ABC transporter, ATPase component" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGV7 at UniProt or InterPro

Protein Sequence (269 amino acids)

>Atu4598 ABC transporter permease (Agrobacterium fabrum C58)
MLQKKNDVKAYEPGVLLEGVSKYFRHADAPVVALEKLDLTIGGGEFVAIVGPSGCGKSTM
MRLISRLSQASTGQISVFGDVSKDPPRGMSIVFQNHVLLAWRTIIDNVLFPAEMTGRNRE
ELRPHALALLESVGLKDFANRYPHELSGGMKQRASIARALLLQPRLLLMDEPFGALDALT
REQMRIDLEALWLKNRMTVVFITHSIDEAVLLADRVIVMTPRPGRIEKVLEIDMPRPRGL
AARREPEFIEKSEEITEIFLSRGILQRHA