Protein Info for Atu4577 in Agrobacterium fabrum C58

Annotation: ABC transporter substrate binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13531: SBP_bac_11" amino acids 31 to 282 (252 residues), 107.9 bits, see alignment E=1.4e-34 PF01547: SBP_bac_1" amino acids 38 to 275 (238 residues), 73.2 bits, see alignment E=7.9e-24 PF13416: SBP_bac_8" amino acids 48 to 292 (245 residues), 91.8 bits, see alignment E=1.3e-29 PF13343: SBP_bac_6" amino acids 93 to 287 (195 residues), 110.1 bits, see alignment E=2.5e-35

Best Hits

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 100% identity to atu:Atu4577)

Predicted SEED Role

"Ferric iron ABC transporter, iron-binding protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CVB1 at UniProt or InterPro

Protein Sequence (330 amino acids)

>Atu4577 ABC transporter substrate binding protein (Agrobacterium fabrum C58)
MRQSCTIFARLVAGATFLASAAFAHAEGTVVVYSAAPQQLMDELLPLFEKKTGTKVELVK
AGSGELMNRIKAETGKAAGDVIWSVDGTVIDFSADLFEPYKPVEAASINPAFSPSTNWVP
FTAVVTAFIVNKEALKGAPVPTSWADLAKPEYKGLISSARADQSGSAYIQMATVLQDFDS
EEKGWEIYTGILGNSVLSTSSGAVPRFVNDGEQAVGITLEDAALRYKLGSAPVEIVYPKE
GTAIAPDGMALVKGGPNSENGKAFIDFIVSKEAQEVVVKAGRRSVRTDVPANVALVPLSD
VPDAKYDFKWAADNRSRLMEKWNDILLDVQ