Protein Info for Atu4502 in Agrobacterium fabrum C58

Annotation: cobalamin synthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 PF02492: cobW" amino acids 11 to 187 (177 residues), 207.3 bits, see alignment E=1.5e-65 PF07683: CobW_C" amino acids 281 to 372 (92 residues), 89.1 bits, see alignment E=1.4e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu4502)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGR3 at UniProt or InterPro

Protein Sequence (375 amino acids)

>Atu4502 cobalamin synthesis protein (Agrobacterium fabrum C58)
MTETAPAKPIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEIGIDNDLIVESD
EEIYEMNNGCVCCTVRGDLIRVVEGLMRRPGRFDGIIVETTGLADPVPVAQTFFMDDDVR
AKTELDAVVALVDAKHLPLRLKDSREAEDQIAFADVVVVNKTDLVTPEEVARIEDIVRAI
NPSARIYKTTRSGVDLARVLDQGAFNLERALENDPHFLEHGHEDHACGPDCDHHHHDHGH
DHGHDHHHHDHDHGHHDHAHDHGHDHHHGAVSPIHDVTVQSVSLRGGEMNPERFFPWIQK
VTQTDGPNILRLKGIIAFKGDAERYVVQGVHMIIEGDHQRPWKEDEKRESRLVFIGRELD
REKLENSFKACLATA