Protein Info for Atu4500 in Agrobacterium fabrum C58

Annotation: MFS permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 33 to 58 (26 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 99 to 116 (18 residues), see Phobius details amino acids 120 to 145 (26 residues), see Phobius details amino acids 160 to 181 (22 residues), see Phobius details amino acids 187 to 209 (23 residues), see Phobius details amino acids 230 to 255 (26 residues), see Phobius details amino acids 267 to 286 (20 residues), see Phobius details amino acids 297 to 318 (22 residues), see Phobius details amino acids 323 to 324 (2 residues), see Phobius details amino acids 330 to 348 (19 residues), see Phobius details amino acids 357 to 377 (21 residues), see Phobius details amino acids 385 to 404 (20 residues), see Phobius details PF07690: MFS_1" amino acids 35 to 269 (235 residues), 36.3 bits, see alignment E=3.3e-13 PF12832: MFS_1_like" amino acids 42 to 367 (326 residues), 45 bits, see alignment E=8.3e-16

Best Hits

KEGG orthology group: K03291, MFS transporter, SET family, sugar efflux transporter (inferred from 100% identity to atu:Atu4500)

Predicted SEED Role

"Sugar efflux transporter B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CV41 at UniProt or InterPro

Protein Sequence (410 amino acids)

>Atu4500 MFS permease (Agrobacterium fabrum C58)
MMVAPNPLPAASLQSIPMLQKSTSPGAFDRQAYLIALLVFIAGSTNAAVVPFIGFYIIQV
LGHPPATLGLYSVTAMVASIIASRFYGERVDAGVRVRPLLLLSVFGAFVAAAAATSGHLA
LLVAVTATGMGLSNAASTLIFSYGRYYGRVNALDAPSYNAVLRTMVSLAWMLLPAAAYLI
LDFAGAKAVFINAMMMAAIWAGLALAIVPRGQTCPMERRADGDADTRRNLPLLMAAAASF
CMSFAHALCASALPVFLVREVGLPDYVPGLSLSVKCAMEVLLILLAPRIMRRVSARILLG
VSAVMAIIAFNIIASVQTLPAMLFGAAMEGAYYGLCAGTCLTFVQGFARGRTARATALYM
NSIFLAGLFAVPLMGFVSQYASFGTSIRLASVGAGAALLLLFLTRRQVSE