Protein Info for Atu4422 in Agrobacterium fabrum C58

Annotation: spermidine/putrescine ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 9 to 31 (23 residues), see Phobius details amino acids 65 to 87 (23 residues), see Phobius details amino acids 95 to 118 (24 residues), see Phobius details amino acids 140 to 166 (27 residues), see Phobius details amino acids 201 to 223 (23 residues), see Phobius details amino acids 244 to 265 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 140 to 269 (130 residues), 51.2 bits, see alignment E=6.6e-18

Best Hits

Swiss-Prot: 36% identical to POTB_HAEIN: Spermidine/putrescine transport system permease protein PotB (potB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02054, putative spermidine/putrescine transport system permease protein (inferred from 100% identity to atu:Atu4422)

Predicted SEED Role

"Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGM1 at UniProt or InterPro

Protein Sequence (275 amino acids)

>Atu4422 spermidine/putrescine ABC transporter permease (Agrobacterium fabrum C58)
MFQNRAEALALALPAAIFAAAVFLVPVFMLLSEGFRTTDGWTLSAYAAFFSDPLNQTVFL
RTLKLGALVTVVSAVVGYAAAFAIINLSPGKKGHVVNLVVLPLMISPVARTYAWIVILGR
TGIVNQALQAVGLSDAPIRILFSETAVFIGLLQLFLPLMIISLISALENMPKDTIAAARV
LGANWFQVFWKVILPLTKEGLVVGGTLVFTGSLTAYITPAILGGSKVLMLETLLYQQVTV
SNNFVAASVIAFILIVMSFAANILLKRIATARNKK