Protein Info for Atu4358 in Agrobacterium fabrum C58

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 PF00005: ABC_tran" amino acids 20 to 162 (143 residues), 114.9 bits, see alignment E=6.7e-37 PF17912: OB_MalK" amino acids 236 to 288 (53 residues), 45.3 bits, see alignment 2e-15 PF08402: TOBE_2" amino acids 281 to 350 (70 residues), 32.9 bits, see alignment E=8.9e-12

Best Hits

Swiss-Prot: 51% identical to UGPC_CUPNH: sn-glycerol-3-phosphate import ATP-binding protein UgpC (ugpC) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 100% identity to atu:Atu4358)

Predicted SEED Role

"Probable ABC transporter ATP-binding protein y4oS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGH7 at UniProt or InterPro

Protein Sequence (361 amino acids)

>Atu4358 ABC transporter permease (Agrobacterium fabrum C58)
MTFQIELSGVNKYYGAFHALKNIDLSIKKGTFVALVGPSGCGKSTLLRSLAGLESISAGD
MRIAGTLMNGVPPRKRDVAMVFQSYALYPHMTVEENLTYSLRMRGVAKAEARKAAEEVAA
TTGLSKLMKRYPRELSGGQRQRVAMSRAIIRNPQAFLFDEPLSNLDAALRVHMRKEIRAL
HDRLHATSVYVTHDQIEAMTMADHVVVMRDGVIEQQGTPLELYDRPVNRFVAGFIGSPAM
NFIPAMVSSDGASLLLQFGEGEPQQSIRAPAPLPPGKRIIVGIRPEHIRPATATGAALTL
PVSTVETTGSATFLTLGTTTEVVIAIQGRSEVRSGEVVGLDINPTDLHLFDEETGAGLGG
R