Protein Info for Atu4294 in Agrobacterium fabrum C58

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 PF00248: Aldo_ket_red" amino acids 14 to 256 (243 residues), 185.1 bits, see alignment E=8e-59

Best Hits

Swiss-Prot: 38% identical to YTBE_BACSU: Uncharacterized oxidoreductase YtbE (ytbE) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to atu:Atu4294)

Predicted SEED Role

"oxidoreductase, aldo/keto reductase family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGD9 at UniProt or InterPro

Protein Sequence (277 amino acids)

>Atu4294 oxidoreductase (Agrobacterium fabrum C58)
MHNVTANGATIPALGFGTFRIPGSDVLRIVPHALKVGFRHVDTAQIYGNEAEVGEAIANS
GVARGDIFLTTKVWVENYGHDAFIKSVDESLKKLKTDYVDLLLLHWPNEAVSLAEQIGAL
NEVKEAGKVRHIGVSNFNTELMAESVKLSRAPIVTNQIEYHPYLSQDVVIAAARKAGMSV
TGYFGMADGKVFNDPVLRDIGARHGKSVAQVVLRWLVQQEGVIALSKTVGEARVLENFAI
FDFALSADEMAAIHALAVPGGRIVSPDGLAPVWDKAA