Protein Info for Atu4292 in Agrobacterium fabrum C58

Annotation: chloramphenicol resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details transmembrane" amino acids 38 to 58 (21 residues), see Phobius details amino acids 70 to 88 (19 residues), see Phobius details amino acids 95 to 117 (23 residues), see Phobius details amino acids 129 to 152 (24 residues), see Phobius details amino acids 159 to 181 (23 residues), see Phobius details amino acids 202 to 226 (25 residues), see Phobius details amino acids 237 to 255 (19 residues), see Phobius details amino acids 267 to 287 (21 residues), see Phobius details amino acids 293 to 314 (22 residues), see Phobius details amino acids 326 to 348 (23 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details PF07690: MFS_1" amino acids 9 to 325 (317 residues), 166.2 bits, see alignment E=1.5e-52 PF06779: MFS_4" amino acids 13 to 375 (363 residues), 51.4 bits, see alignment E=1.6e-17 PF00083: Sugar_tr" amino acids 39 to 181 (143 residues), 44.9 bits, see alignment E=1.2e-15

Best Hits

Swiss-Prot: 57% identical to YTBD_BACSU: Uncharacterized MFS-type transporter YtbD (ytbD) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to atu:Atu4292)

Predicted SEED Role

"Major facilitator family transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CUJ6 at UniProt or InterPro

Protein Sequence (393 amino acids)

>Atu4292 chloramphenicol resistance protein (Agrobacterium fabrum C58)
MPLAIFALTIAAYAIGTTEFVIVGLLPTVANDLHITLPLAGLIVSVYALGVTFGAPILTA
LTGRIERKPLLLGLMALFIVGNTAAALSPSYEMLLVARVIAAFAHGVFFSVGATIAADLV
PENRRASAIAMMFMGLTVAIVTGVPIGTYIGQIFGWRATFWAVGALGIVAFVAIAVLLPN
TLKKAPPASIFDQVRVLGSGRLLIVFAMTALGYGGTFVAFTFLAPILQDVTGFSESSVSL
ILVLYGIAIAAGNIGGGKIANHNPVKALIGLFALQAIVLVIFSFTAVSPVLTLITLVALG
FLSFANVPGLQLYVVQLAKEHRPGAVDVASALNIAAFNLGIALGAWLGGVVVESPMGLGA
TPWVGAILVAVALLLTIWSGALDRRAAPVLKAA