Protein Info for Atu4262 in Agrobacterium fabrum C58

Annotation: ABC transporter substrate binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF09084: NMT1" amino acids 9 to 229 (221 residues), 84.9 bits, see alignment E=8.1e-28 PF13379: NMT1_2" amino acids 11 to 236 (226 residues), 86.5 bits, see alignment E=2.6e-28

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 100% identity to atu:Atu4262)

Predicted SEED Role

"Hydroxymethylpyrimidine ABC transporter, substrate-binding component" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGB8 at UniProt or InterPro

Protein Sequence (309 amino acids)

>Atu4262 ABC transporter substrate binding protein (Agrobacterium fabrum C58)
MSVGSYNLNNLPFPVAASLGFYKDEGLDVTTENFAQGGSKVLQALVAGSTDVAVGFYDHT
IQMQSQNKHVVGFVQLARNSGLVLAGTNDTDFDPAKPETIKGKKVGITSPGSSSDFFIRY
YMKQHNLSDNDISIIGVGSGAAAVAALQQGKIDLLVNYDPAATIVVERGLGKILIDARSD
QGAKDVYGGIYPTSVLYATQDYINANPEVIQKVTNATVRALHWMKQHSAEEIVAKLPDDF
VSGDKQTYIKAVEAAKAIFSEDGKFEPADLETPLAVLKSFNDAVAKATIDLNTTYTNKFV
EAAASKGGN