Protein Info for Atu4123 in Agrobacterium fabrum C58

Annotation: branched chain amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 28 to 365 (338 residues), 356.6 bits, see alignment E=3.2e-110 PF13433: Peripla_BP_5" amino acids 29 to 357 (329 residues), 64.8 bits, see alignment E=1.2e-21 PF01094: ANF_receptor" amino acids 50 to 335 (286 residues), 30.3 bits, see alignment E=3.6e-11

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 100% identity to atu:Atu4123)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CG38 at UniProt or InterPro

Protein Sequence (402 amino acids)

>Atu4123 branched chain amino acid ABC transporter substrate-binding protein (Agrobacterium fabrum C58)
MRKSIVLSTAMALAAGTAAYAAEISDGKVKIGILNDQSGVYANFGGKYSYEAAKMAVEDF
GGKVLGAPVEVVTADHQNKADVASNIARQWYDTEQVDSIMELTSSSVGLAVQALSKDKKK
ITVNTGAATTELTGKQCSPYGFHWAYDTYSLAVGTGGALVKQGGDSWFFLTADYAFGYSL
EENTSNFVKANGGKVLGSVRHPLATTDYSSFLLQAQSSGAKVIGLANAGLDTSNAIKQAS
EFGIVAGGQRLAALLFTLAEVHGLGLEAAQGLTLTEGFYWDRDDESRKFGERFKERTGAM
PNMIHTGTYSAVLHYLKAIEKAGTDDADAVAKAMKEMPVNDVFAKDGHVAANGRMIHDMY
LMEVKKPDESKQPWDYYKVLATIPGKEAFMDPTKSGCPLVKQ