Protein Info for Atu4115 in Agrobacterium fabrum C58

Annotation: dipeptide ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 transmembrane" amino acids 35 to 56 (22 residues), see Phobius details amino acids 103 to 130 (28 residues), see Phobius details amino acids 148 to 175 (28 residues), see Phobius details amino acids 218 to 245 (28 residues), see Phobius details amino acids 266 to 289 (24 residues), see Phobius details PF12911: OppC_N" amino acids 23 to 72 (50 residues), 56.5 bits, see alignment 2e-19 PF00528: BPD_transp_1" amino acids 119 to 302 (184 residues), 123.1 bits, see alignment E=1.1e-39

Best Hits

Swiss-Prot: 62% identical to DPPC_ECO57: Dipeptide transport system permease protein DppC (dppC) from Escherichia coli O157:H7

KEGG orthology group: K12370, dipeptide transport system permease protein (inferred from 100% identity to atu:Atu4115)

MetaCyc: 62% identical to dipeptide ABC transporter membrane subunit DppC (Escherichia coli K-12 substr. MG1655)
ABC-8-RXN [EC: 7.4.2.9]

Predicted SEED Role

"Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CG33 at UniProt or InterPro

Protein Sequence (304 amino acids)

>Atu4115 dipeptide ABC transporter permease (Agrobacterium fabrum C58)
MTDVITTPGVRLSDAAIRRRMIADFWFYFRQNRGAVIGLAVFILLVLIAVFAAVIAPHDP
TQQYRDALLVPPVWQDGGRAAFLLGTDAVGRDMLSRLIYGAQYSLFIGVVVVSIALVGGI
VIGLVAGFFGGWVDTVIMRVMDVILAFPSLLLALVLVAILGPGLTNAMIAIAIVYQPHFA
RLTRAAVMSELRREYVTAARVAGAGNLRLMFKTILPNCLAPLIVQATLSFSSAVLDAAAL
GFLGMGAQPPASEWGTMLAEAREFILRAWWVVTLPGLTILISVLAINLMGDGLRDALDPK
LKRS