Protein Info for Atu4097 in Agrobacterium fabrum C58

Annotation: L-aspartate oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details PF00890: FAD_binding_2" amino acids 12 to 377 (366 residues), 274.4 bits, see alignment E=2.1e-85 TIGR00551: L-aspartate oxidase" amino acids 12 to 484 (473 residues), 478.3 bits, see alignment E=1.3e-147 PF02910: Succ_DH_flav_C" amino acids 461 to 492 (32 residues), 26.8 bits, see alignment (E = 4.4e-10)

Best Hits

Swiss-Prot: 100% identical to NADB_AGRFC: L-aspartate oxidase (nadB) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K00278, L-aspartate oxidase [EC: 1.4.3.16] (inferred from 100% identity to atu:Atu4097)

Predicted SEED Role

"L-aspartate oxidase (EC 1.4.3.16)" in subsystem NAD and NADP cofactor biosynthesis global or NAD regulation (EC 1.4.3.16)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8U8J4 at UniProt or InterPro

Protein Sequence (522 amino acids)

>Atu4097 L-aspartate oxidase (Agrobacterium fabrum C58)
MSEFLPQRDWTVIVGSGMAGLMAAMTLAPQPVLLVTRGALGGETSSAWAQGGIAASLGPD
DRAALHVADTLAAGDGLCDEDMVVGIVSSAPAVIDALERAGVRFDRDAGGNYVFGLEAAH
SRRRILHAEGDGSGAAIVRALTDAVRRTPSITVLEGTEVRRLLTEDSVIAGLACAGPNGS
FLLPASQVILATGGLGGLYDATTNPSGNFGQGIMLAARAGAILADMEFVQFHPTALSSPR
RPLALVSEAVRGEGALLLNENGERFMAAVPGAELASRDIVARAIDREILRGGQVFLDARQ
ALGSGFASRFPSIDLLCREAGIDPARELVPVRPAVHYHMGGVATDNKGRSSVRGLWVAGE
TACTGLHGANRLASNSLLEAAAMGMRAAQDIAGRPAPAARSAAAVSPNATADFSPADLAA
VRPIVSRHLGIVRHAAGLAEAIRDLLPLAERNGPASDPAVVALSIAVFAALRRESRGAHF
RDDFSQKDAKAMRRRLSLNDVVTVAHEFSSSSLATAGFARSA