Protein Info for Atu4023 in Agrobacterium fabrum C58

Annotation: ferrichrome ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01497: Peripla_BP_2" amino acids 31 to 265 (235 residues), 82.5 bits, see alignment E=1.7e-27

Best Hits

KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 100% identity to atu:Atu4023)

Predicted SEED Role

"Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), periplasmic substrate binding protein FhuD" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin (TC 3.A.1.14.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CTW0 at UniProt or InterPro

Protein Sequence (293 amino acids)

>Atu4023 ferrichrome ABC transporter substrate-binding protein (Agrobacterium fabrum C58)
MSPLWGRREFLGMLAASAFAGTARAKQTPRIAAIDWAMLETSVALGVMPVAATELIQFRA
GAVEPDIPESVADLGLRGAPNFELLQLTRPDLILISPFYTRYTGRLEAIAPVFSLPFYVK
GEPPFEKALAAVTALGEKLGRTDEARKVLIETDAAMQAMRTRLAGFSARPTYVINIGDAR
HFRAFGADSMFGDILSRLGLANAWVDRSQFTFAAPVPLENLAASPEARIVIVSDIPVEAR
EGLRNSAIWRALPAVRQGRVVTLGNVGPYGGITAGMRFARLLTEALTAQGEAL