Protein Info for Atu3916 in Agrobacterium fabrum C58

Annotation: exogenous ferric siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 702 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF07715: Plug" amino acids 60 to 169 (110 residues), 94.9 bits, see alignment E=4.2e-31 PF00593: TonB_dep_Rec_b-barrel" amino acids 229 to 675 (447 residues), 219.2 bits, see alignment E=2e-68

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to atu:Atu3916)

Predicted SEED Role

"TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CTM1 at UniProt or InterPro

Protein Sequence (702 amino acids)

>Atu3916 exogenous ferric siderophore receptor (Agrobacterium fabrum C58)
MELKYRGQNRTATIIKAGVSAAMAGTALGFAVPAFAQQASEGNTVLQQIVVTASGFEQNV
KDAPASITVVTREDLEKGSYRDLTDALREVQGVSVTGIANEKDVFIRGLPGAYTLILVDG
KRQSTRDARTNGNSGFEQSFVPPVSAIERIEVVRGPMSSLYGSDAMGGVINIITRKVGDV
WSGSVTTEGTVQQHSKFGNSGQVSWYANGPILKDQLGLQLWGRGFTRGEDRILNGTTGAK
EYDFNGRLTFTPNEDHDIYLEGGKTRLRRDAEPGDTLAATDANGTYNTNTRDHWSLSHTG
RWGPTTSEFSFQQEWAERTNFTRNTRTGRVTENPRSPEIRNTVLDGKFTTPFELFGNHTL
VTGGQYFEARLTDQNPGRRTDRDETFSATQWALFLEDEWRIVDNFALTGGLRLDNHEKYG
NHFSPRLYGVWSATEELTIKGGVSTGFRAPEIRQIAPGYAYTTGGGGCSYGPSGTCGVII
GDPNLEAEKSTSYEIAALWDNGDIALGATYFYTDFKDKISNALVLNPDGTPARWSEDRNY
RLWYNYNIDDAIIQGVELTATWYATSELTLRGNYTYTHSEQKTGDYEGFPLARTPEHMAN
LRGDWVTPIDGLEAWVSLNYHGSEINAGPRIGANGTPVTINGQSGRKYDAYTTLDIGAKY
AVAENVDLNAAVYNVFDKDVGTDDFNTVMEGRRFWISMTAKF