Protein Info for Atu3874 in Agrobacterium fabrum C58

Annotation: L-xylulose kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00370: FGGY_N
  • amino acids 2 to 243 (242 residues), 166 bits, E=1.2e-52
• PF02782: FGGY_C
  • amino acids 253 to 436 (184 residues), 96.5 bits, E=1.9e-31

Best Hits

KEGG orthology group: K00880, L-xylulokinase [EC: 2.7.1.53] (inferred from 100% identity to atu:Atu3874)

Predicted SEED Role

"Erythritol kinase EryA (EC 2.7.1.27)" in subsystem Erythritol utilization (EC 2.7.1.27)

MetaCyc Pathways

• L-lyxose degradation (1/4 steps found)
• superpathway of pentose and pentitol degradation (16/42 steps found)

KEGG Metabolic Maps

• Ascorbate and aldarate metabolism
• Pentose and glucuronate interconversions

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.27 or 2.7.1.53

Sequence Analysis Tools

See Q7CTI2 at UniProt or InterPro

Protein Sequence (492 amino acids)

>Atu3874 L-xylulose kinase (Agrobacterium fabrum C58)
MGLDVGNTVIKAVLFDTAGRQIAQHAIDGHSTYPQPGYVERDLEELWRNGCEAIRQLLVK
SAVDPNSIAGVGCAGHGNGLYLLDKEQQPLLGIQSLDSRAADMAAELDRKSGDLLQARCL
QRPWPAQTPTLLAWVKRHALDLYAQTSTVLFCKDFINFRLTGCLANDISDLSGAGLLALP
EVLLDRELLSLYGLEDAFAFFPRCVESADIVGQVTREAAGLTGLSEGTPVIGGFFDVVSS
AMGSGVINPGEASVIAGTWSINQVFADKPVVSPDVFMVTTFGRDRYVNIESSATSAANLE
WYVHRVRADHGDHAFERCNELVGSVTPRADDPFFHPFIFGSRLGAEFRGGFYGLAGWHGE
GHMVRALFEGVCFEHRRHIGVLREAGLPVESAVMSGGGSRSQHWPQIMADVLEIPLRVAE
ARETGALGAALGAAVATGLYPNYEEAVAAMTRVQNSYQPDTARVSHYRRRYGLYQELTGQ
LRSFWSALRLPQ