Protein Info for Atu3726 in Agrobacterium fabrum C58

Annotation: flavin dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 PF00296: Bac_luciferase" amino acids 4 to 298 (295 residues), 134.7 bits, see alignment E=2.4e-43 TIGR03558: luciferase family oxidoreductase, group 1" amino acids 4 to 324 (321 residues), 439.1 bits, see alignment E=5.1e-136

Best Hits

Swiss-Prot: 52% identical to YHBW_ECOLI: Luciferase-like monooxygenase (yhbW) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to atu:Atu3726)

Predicted SEED Role

"Flavin dependant oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CFK5 at UniProt or InterPro

Protein Sequence (333 amino acids)

>Atu3726 flavin dependent oxidoreductase (Agrobacterium fabrum C58)
MIPFSILDLSPIGEGESVSAALENSRRMAIKAEEHGYNRLWLAEHHGMPGIASAATSLVI
AHVGAATKHIRVGSGGIMLPNHSPLVIAEQFGTLAALLPGRVDLGLGRAPGTDMRTARAL
RRNLDAGAENFPHDIVELQRYLGPPQPDQAILAVPGMNSNVPLWLLGSSTYSAHLAAALG
LPYSFASHFAPDMLMEAIHIYRERFQPSEVLDKPYVMVGVMGVGADTDEEAQHLFTSSQQ
QFVNLRRNVRTQFPKPVHSMDDYWNEMERFSVEHTLRFAAVGSPETIERHLDGFLAETQA
DELIVSMPIHDIEKRLRSVEIFADVRTAIRKAA