Protein Info for Atu3711 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 TIGR02432: tRNA(Ile)-lysidine synthetase" amino acids 31 to 217 (187 residues), 137.5 bits, see alignment E=2.5e-44 PF01171: ATP_bind_3" amino acids 31 to 215 (185 residues), 135 bits, see alignment E=1.2e-43

Best Hits

Swiss-Prot: 100% identical to TILS_AGRFC: tRNA(Ile)-lysidine synthase (tilS) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K04075, tRNA(Ile)-lysidine synthase [EC: 6.3.4.-] (inferred from 100% identity to atu:Atu3711)

Predicted SEED Role

"tRNA(Ile)-lysidine synthetase (EC 6.3.4.19)" (EC 6.3.4.19)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.4.- or 6.3.4.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8U9L7 at UniProt or InterPro

Protein Sequence (443 amino acids)

>Atu3711 hypothetical protein (Agrobacterium fabrum C58)
MPVDARTPNEKTVAPLAAASAFVESLRKPTHILVAISGGSDSTGLLLALQEAKAADDDGL
RLSAVTVDHALRPESADEARKVAMLCAELGIPHTTRRWDGPKPASGLSEASRLARYRLIA
DVAREIGADLVVSGHTIGDQRETVAMRAARSGGSDNLGLSGMADAVLYDAHLWIMRPFLA
CERQVIRDYVSSRSRHWLDDPSNENIRYERVRVRQTLPHSPIALDDSTAVRRQMLSERTA
VFLRERAQVFHAALARLADDDVNPDLPEFRHGLAALIAALGGRSYFPAASSMERVLRFLK
TGETGRMTVGRVLLDRRRDGLYIFREQRNLPELQIESSGQAVWDDRFLVKNGSDFPINVA
AGRVGTAAQAAALFPSAPSGVVKPAMAGLPQIAAAAEGWVSTPEVAITPRLAPFDLFLPR
FDLELANAIANLFGRPAYPQPPV