Protein Info for Atu3503 in Agrobacterium fabrum C58

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 transmembrane" amino acids 17 to 40 (24 residues), see Phobius details amino acids 60 to 84 (25 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 188 to 206 (19 residues), see Phobius details amino acids 213 to 236 (24 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details TIGR02139: sulfate ABC transporter, permease protein CysT" amino acids 9 to 272 (264 residues), 405.2 bits, see alignment E=1.4e-125 TIGR00969: sulfate ABC transporter, permease protein" amino acids 9 to 269 (261 residues), 318.2 bits, see alignment E=4.6e-99 PF00528: BPD_transp_1" amino acids 75 to 269 (195 residues), 64.5 bits, see alignment E=5.5e-22

Best Hits

Swiss-Prot: 59% identical to CYST_SALTY: Sulfate transport system permease protein CysT (cysU) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02046, sulfate transport system permease protein (inferred from 100% identity to atu:Atu3503)

MetaCyc: 58% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysU (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysT" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CSM5 at UniProt or InterPro

Protein Sequence (277 amino acids)

>Atu3503 ABC transporter permease (Agrobacterium fabrum C58)
MGAGLKRNVLPGLKLSLGVTLTYVAIIVLLPLSALVFKAASLGPAEYWSIISSPRAVASY
RVTVLCALAATLFNVVFGVALAWVLTRYRFPGWRIVDAIVDLPFALPTAVAGIALTTLFA
GNGWFGSLLAPLGIKVAYTPVGIMVAMAFTSLPFIVRTVQPVLEDLDPALEEAAQSLGGS
DLEVFRKIILPLLTPALLAGLSLSFARSLGEFGAIIFIAGNQPFSTEITALLIFIRLEEY
DYQAAAAIASVLLITAFVMLAVTNYLQARALRYTVRS