Protein Info for Atu3435 in Agrobacterium fabrum C58

Annotation: oligopeptide ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 transmembrane" amino acids 61 to 87 (27 residues), see Phobius details amino acids 131 to 155 (25 residues), see Phobius details amino acids 176 to 203 (28 residues), see Phobius details amino acids 248 to 272 (25 residues), see Phobius details amino acids 292 to 314 (23 residues), see Phobius details PF12911: OppC_N" amino acids 58 to 92 (35 residues), 26.7 bits, see alignment 4.2e-10 PF00528: BPD_transp_1" amino acids 145 to 327 (183 residues), 105.4 bits, see alignment E=3.1e-34

Best Hits

Swiss-Prot: 40% identical to DPPC_ECO57: Dipeptide transport system permease protein DppC (dppC) from Escherichia coli O157:H7

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 100% identity to atu:Atu3435)

MetaCyc: 40% identical to dipeptide ABC transporter membrane subunit DppC (Escherichia coli K-12 substr. MG1655)
ABC-8-RXN [EC: 7.4.2.9]

Predicted SEED Role

"Putative glutathione transporter, permease component" in subsystem Utilization of glutathione as a sulphur source

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CF73 at UniProt or InterPro

Protein Sequence (331 amino acids)

>Atu3435 oligopeptide ABC transporter permease (Agrobacterium fabrum C58)
MNSSHTSAVLNTAELGAEETNPKPKKPEEKVWPYIHAPDALSARSVSVPRRGLRRELKIF
LTNPNAIVGLLFLATVLIAALIAPLIYPGDPLEMVARPFLWPGQNAAYPLGTDSMGRDVL
AGIVHGARISLTVGVVATLIGLTIGISIGAFAGYFGGVIDDILVKLIEIFQTLPNFVLLV
VLVAIAQPSVTTVTSAIGIITWPLVARLTRAEFRAIREKDYVLAARSLGYGHARIVFQEI
LPNALPPIIVTSSVMVAGAILMEAALSFMGLGDPNRVSWGSMIGSGRDVIRTAWYLTALP
GLAIVFTVISLNLISDGLNDALNPRFSEERR