Protein Info for Atu3360 in Agrobacterium fabrum C58

Annotation: amino acid ABC transporter ATPase/permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 PF00005: ABC_tran" amino acids 34 to 184 (151 residues), 132.6 bits, see alignment E=3.1e-42 PF02463: SMC_N" amino acids 46 to 223 (178 residues), 40.9 bits, see alignment E=3.2e-14

Best Hits

Swiss-Prot: 51% identical to NOCP_AGRFC: Nopaline permease ATP-binding protein P (nocP) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 100% identity to atu:Atu3360)

MetaCyc: 51% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"amino acid ABC transporter, ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21 or 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CS95 at UniProt or InterPro

Protein Sequence (271 amino acids)

>Atu3360 amino acid ABC transporter ATPase/permease (Agrobacterium fabrum C58)
MSAPAPQNAAQAPVTKALVELEGIHLSFGDNQVLKGIDLTVNKGDAVSIIGPSGSGKSTI
LRCINGLLIPQSGKITVGGTRVDQLKTEAERIALRKRIGIVFQQFNLFPHLTVMENITIA
PIKILGTPKAEAERHARELLEKVRLSQKVDAYPGQLSGGQQQRVAIARALAMRPELVLFD
EVTSALDPETVGEVLAVIRDLVNDGMTSILVTHEMRFAEEISDKIVFTENGLIVDQGTPE
HIFYRSTNPRINAFVKGLGGQVARVTDGEGI