Protein Info for Atu3338 in Agrobacterium fabrum C58

Annotation: trehalose/maltose ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR01414: outer membrane autotransporter barrel domain" amino acids 10 to 186 (177 residues), 16.3 bits, see alignment E=2.1e-07 PF01547: SBP_bac_1" amino acids 37 to 331 (295 residues), 136.1 bits, see alignment E=2.8e-43 PF13416: SBP_bac_8" amino acids 43 to 355 (313 residues), 117 bits, see alignment E=1.4e-37

Best Hits

KEGG orthology group: K10236, trehalose/maltose transport system substrate-binding protein (inferred from 100% identity to atu:Atu3338)

Predicted SEED Role

"Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE" in subsystem Bacterial Chemotaxis or Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CF11 at UniProt or InterPro

Protein Sequence (421 amino acids)

>Atu3338 trehalose/maltose ABC transporter substrate-binding protein (Agrobacterium fabrum C58)
MNISMKTLFLCGVAFSAAISAEAAELSIAANSTGKNVAFFRERIAAFEKETGHKVNLVTM
PSSSSEQFSQYRLWLAAGNKDVDVYQTDVIWAPQLAEQFVDLTAATKDVIGDHFPSIVAS
QTVDGKLVAMPMFTDAPALFYRKDLLEKYGKQPPKTWKELSETAKEVQDKERAAGQKDLW
GFVFQGSAYEGLTCNALEWIASAGGGHIVETNGDISINNEKAAAAIETAKGWVGTIAPQG
VLAYKEEEARGVWQTGNSVFMRNWPYAYALGNGADSAIKDKFGVTPLPAGEEGAAPASTL
GGWNLAVSKYSDDQEAAIQLVKFLASKDTQKLRAIQLSNMPTIASLYDDKDVAAAQPFMP
TWKPIFETAVPRPSASAKVKYNEVSAKFWGAVHNTLSGNGTAAENLELLEVELTDLKGNG
W