Protein Info for Atu3309 in Agrobacterium fabrum C58

Annotation: cellulose synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 729 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 29 to 46 (18 residues), see Phobius details amino acids 52 to 70 (19 residues), see Phobius details amino acids 90 to 111 (22 residues), see Phobius details amino acids 401 to 424 (24 residues), see Phobius details amino acids 436 to 454 (19 residues), see Phobius details amino acids 512 to 531 (20 residues), see Phobius details amino acids 543 to 562 (20 residues), see Phobius details amino acids 689 to 711 (23 residues), see Phobius details TIGR03030: cellulose synthase catalytic subunit (UDP-forming)" amino acids 2 to 713 (712 residues), 1031.3 bits, see alignment E=0 PF13641: Glyco_tranf_2_3" amino acids 128 to 374 (247 residues), 83.7 bits, see alignment E=6.2e-27 PF00535: Glycos_transf_2" amino acids 132 to 319 (188 residues), 93 bits, see alignment E=6.2e-30 PF13506: Glyco_transf_21" amino acids 208 to 372 (165 residues), 35.1 bits, see alignment E=2.8e-12 PF13632: Glyco_trans_2_3" amino acids 230 to 423 (194 residues), 82 bits, see alignment E=1.7e-26 PF03552: Cellulose_synt" amino acids 326 to 441 (116 residues), 35 bits, see alignment E=1.9e-12 PF07238: PilZ" amino acids 569 to 671 (103 residues), 31.8 bits, see alignment E=4.4e-11

Best Hits

KEGG orthology group: K00694, cellulose synthase (UDP-forming) [EC: 2.4.1.12] (inferred from 100% identity to atu:Atu3309)

Predicted SEED Role

"Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.12

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CEZ7 at UniProt or InterPro

Protein Sequence (729 amino acids)

>Atu3309 cellulose synthase (Agrobacterium fabrum C58)
MNKAITVIVWLLVSLCVLAIITMPVSLQTHLVATAISLILLATIKSFNGQGAWRLVALGF
GTAIVLRYVYWRTTSTLPPVNQLENFIPGFLLYLAEMYSVVMLGLSLVIVSMPLPSRKTR
PGSPDYRPTVDVFVPSYNEDAELLANTLAAAKNMDYPADRFTVWLLDDGGSVQKRNAANI
VEAQAAQRRHEELKKLCEDLDVRYLTRERNVHAKAGNLNNGLAHSTGELVTVFDADHAPA
RDFLLETVGYFDEDPRLFLVQTPHFFVNPDPIERNLRTFETMPSENEMFYGIIQRGLDKW
NGAFFCGSAAVLRREALQDSDGFSGVSITEDCETALALHSRGWNSVYVDKPLIAGLQPAT
FASFIGQRSRWAQGMMQILIFRQPLFKRGLSFTQRLCYMSSTLFWLFPFPRTIFLFAPLF
YLFFDLQIFVASGGEFLAYTAAYMLVNLMMQNYLYGSFRWPWISELYEYVQTVHLLPAVV
SVIFNPGKPTFKVTAKDESIAEARLSEISRPFFVIFALLLVAMAFAVWRIYSEPYKADVT
LVVGGWNLLNLIFAGCALGVVSERGDKSASRRITVKRRCEVQLGGSDTWVPASIDNVSVH
GLLINIFDSATNIEKGATAIVKVKPHSEGVPETMPLNVVRTVRGEGFVSIGCTFSPQRAV
DHRLIADLIFANSEQWSEFQRVRRKNPGLIRGTAIFLAIALFQTQRGLYYLVRARRPAPK
SAKPVGAVK