Protein Info for Atu3279 in Agrobacterium fabrum C58
Annotation: methanesulfonate sulfonatase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K04091, alkanesulfonate monooxygenase [EC: 1.14.14.5] (inferred from 100% identity to atu:Atu3279)MetaCyc: 100% identical to sulfoquinovose monooxygenase monomer (Agrobacterium fabrum)
RXN-22961 [EC: 1.14.14.181]
Predicted SEED Role
"Aliphatic sulfonate monooxygenase family, FMNH2- or F420-dependent"
MetaCyc Pathways
- sulfoquinovose degradation IV (2/2 steps found)
- two-component alkanesulfonate monooxygenase (2/2 steps found)
Isozymes
Compare fitness of predicted isozymes for: 1.14.14.5
Use Curated BLAST to search for 1.14.14.181 or 1.14.14.5
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A9CEY7 at UniProt or InterPro
Protein Sequence (385 amino acids)
>Atu3279 methanesulfonate sulfonatase (Agrobacterium fabrum C58) MTVVPVTSADLDAAEVSWFSALCSDDYAYLGVPDGSLRSSFEHCSDIVKKAEELGFRNIL CPSSYQVGQDTLSFVAGCAPISDRINFLAAIRCGEMQPIMLARTVATLDHMLKGRLTLNV ISSDFPGEVADSAFRYKRSHEVVEILRQAWTRDTIDHDGEIYQFKGVSTEPARPYQLNGG PLLYFGGYSPDALELCGAQCDVYLMWPETKDQLADRMRAAHERAAAHGRTLDYGLRVHMV VRDTEQEAREYADHLVSKLDDEYGQLIRNRAHDSGSLGVSHQARARELADKFGYVEPNLW TGIGRARSGCGAALVGSTDQVLSALEEYQKMGIRAFILSGYPHLDEAEHFGTKVLPQMKT CSLPHAYGRVPSETPATPLGNGERH