Protein Info for Atu3246 in Agrobacterium fabrum C58

Annotation: amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00497: SBP_bac_3" amino acids 39 to 269 (231 residues), 160 bits, see alignment E=3.1e-51

Best Hits

Swiss-Prot: 35% identical to GLTI_ECOLI: Glutamate/aspartate import solute-binding protein (gltI) from Escherichia coli (strain K12)

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to atu:Atu3246)

MetaCyc: 35% identical to glutamate/aspartate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-13-RXN [EC: 7.4.2.1]; 7.4.2.1 [EC: 7.4.2.1]

Predicted SEED Role

"Glutamate Aspartate periplasmic binding protein precursor GltI (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CEX1 at UniProt or InterPro

Protein Sequence (300 amino acids)

>Atu3246 amino acid ABC transporter substrate-binding protein (Agrobacterium fabrum C58)
MQRSTLWLLLFFLSFLPVAAASDNAQPPTLETIARTGTIRLGFADRNIPFSYLGTGPEPI
GYSIELCLRVADSIKRKLALPELKVEFVKRTPSNRIMLLNDGTIDMECVASTNTEERRKA
VWFSYSHFITGTRYVALKSSGLNTVADLAGRTVVVTTGTINISQLNVLNRKLGMNIAVLQ
NDSTEGSFDMVTENRASAFVMDDILLRSFIAETGRPEDYVISNEYLAPPQPYGLMLRHGD
TGFRDAVNEALGQIYQSGEIEKIYDKWFNAPIPPNGINLKRPLPGDLAEAFRSPVDTTAE