Protein Info for Atu3085 in Agrobacterium fabrum C58

Annotation: hydantoin racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 PF01177: Asp_Glu_race" amino acids 3 to 209 (207 residues), 187.8 bits, see alignment E=1.2e-59

Best Hits

Swiss-Prot: 47% identical to HYDRA_PSESN: Hydantoin racemase (hyuE) from Pseudomonas sp. (strain NS671)

KEGG orthology group: K01797, [EC: 5.1.99.-] (inferred from 100% identity to atu:Atu3085)

MetaCyc: 48% identical to allantoin racemase monomer (Klebsiella pneumoniae)

Predicted SEED Role

"Allantoin racemase (EC 5.1.99.3)" (EC 5.1.99.3)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 5.1.99.-, 5.1.99.3

Use Curated BLAST to search for 5.1.99.- or 5.1.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CEM9 at UniProt or InterPro

Protein Sequence (247 amino acids)

>Atu3085 hydantoin racemase (Agrobacterium fabrum C58)
MRILVVNPNTTRSMTATIADAAMRVVGRDTEILGVTSSMGPVSIEGYYDEVFAVPGLLLE
LAKAPALGVDAAVIACFDDTGLDAARAFCDIPVIGLCEAAVSATAFIAQKFTIVTTMERS
RLPLEHLVHRYGMSARCNVRAADIPVLSLEDPASNARERLRQEIALALKEDRAEAIVLGC
AGMADLTAELRAEFGVPVVDGVAAAVKQAESLVSMGLSTAKSGAYAKPVAKPYHGLLEAF
RPDRMTA