Protein Info for Atu2666 in Agrobacterium fabrum C58

Annotation: MFS permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 46 to 62 (17 residues), see Phobius details amino acids 72 to 91 (20 residues), see Phobius details amino acids 97 to 118 (22 residues), see Phobius details amino acids 130 to 155 (26 residues), see Phobius details amino acids 161 to 180 (20 residues), see Phobius details amino acids 209 to 235 (27 residues), see Phobius details amino acids 244 to 266 (23 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 304 to 328 (25 residues), see Phobius details amino acids 339 to 359 (21 residues), see Phobius details amino acids 365 to 386 (22 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 2 to 384 (383 residues), 222 bits, see alignment E=8.3e-70 PF07690: MFS_1" amino acids 11 to 352 (342 residues), 137.5 bits, see alignment E=5.5e-44 PF00083: Sugar_tr" amino acids 38 to 183 (146 residues), 28.8 bits, see alignment E=6.1e-11

Best Hits

KEGG orthology group: K03445, MFS transporter, DHA1 family, purine ribonucleoside efflux pump (inferred from 100% identity to atu:Atu2666)

Predicted SEED Role

"putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CHI6 at UniProt or InterPro

Protein Sequence (392 amino acids)

>Atu2666 MFS permease (Agrobacterium fabrum C58)
MSTKRTAILGALLTALAPISMAIYTPAMPELTRVFATNESAIKLSLSLYFAGFALAQLLA
GPASDAFGRRRASLVFLSVFLGGGLLAIFAPTIEVLLLARLIQGIGASVGMTVARAIVRD
QFTGAEASSIMNLIGIMLAVGPALGPTIGGLSLAAFGWKSVFFLMAGLGAAAIFSVVIFL
RETTVPDKSLIRPRRLLSAYGNLLTEPRFLLAALVLGGSIGALYAQATMLTFILINTVGM
TPTAFGIGMLMQTGAYFFGSIALRYIAPRLGDRRSVMLGLCFSGTGGLLILLSVFLIPPS
FFSIMGPVAVATVGIALLTPSMVTAALAPFPHIAGSASAMMGFIQMGSGFAGGTAASLIG
SPLTGFGIVIPVMEFTAVASYIGFRIVSRSKT