Protein Info for Atu2663 in Agrobacterium fabrum C58

Annotation: GTP-binding tyrosin phosphorylated protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 606 TIGR00231: small GTP-binding protein domain" amino acids 2 to 151 (150 residues), 80.6 bits, see alignment E=1.1e-26 TIGR01394: GTP-binding protein TypA/BipA" amino acids 3 to 598 (596 residues), 912.7 bits, see alignment E=8.5e-279 PF00009: GTP_EFTU" amino acids 3 to 194 (192 residues), 194.8 bits, see alignment E=3.2e-61 PF01926: MMR_HSR1" amino acids 6 to 127 (122 residues), 22.5 bits, see alignment E=3e-08 PF22042: EF-G_D2" amino acids 210 to 288 (79 residues), 36.4 bits, see alignment E=1.4e-12 PF03144: GTP_EFTU_D2" amino acids 217 to 288 (72 residues), 51 bits, see alignment E=4.8e-17 PF00679: EFG_C" amino acids 396 to 480 (85 residues), 79.3 bits, see alignment E=5.3e-26 PF21018: BipA_C" amino acids 484 to 592 (109 residues), 154.7 bits, see alignment E=2.1e-49

Best Hits

Swiss-Prot: 55% identical to TYPA_ECOL6: GTP-binding protein TypA/BipA (typA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K06207, GTP-binding protein (inferred from 100% identity to atu:Atu2663)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CHI8 at UniProt or InterPro

Protein Sequence (606 amino acids)

>Atu2663 GTP-binding tyrosin phosphorylated protein (Agrobacterium fabrum C58)
MALRNIAIIAHVDHGKTTLVDELLKQSGSFRDNQRVAERVMDSNDLEKERGITILAKATS
VEWKGVRINIVDTPGHADFGGEVERILSMVDGAIVLVDSSEGPMPQTKFVVSKALKVGLR
PIVAINKIDRPDGRHEEVINEVFDLFANLDATDEQLDFPILYGSGRDGWMNVNPEGPKDQ
GLAPLLDLVLEHVPEPKVEEGPFRLIGTILEANPFLGRIITGRIASGSIKPNQAVKVLGQ
DGKLIETGRISKILAFRGIERTAIEEAHAGDIVAIAGLSKGTVADTFCDPSVTEAMTAQP
IDPPTVTMSFIVNDSPLAGTEGDKVTSRVIRDRLFKEAEGNVALKIEEAEGKDSFFVSGR
GELQLAVLIETMRREGFELAVSRPRVVMHKDENGTLLEPIEEVVIDVDEEHSGVVVQKMS
ERKAEMAELRPSGGNRVRLKFYAPTRGLIGYQSELLTDTRGTAIMNRLFHDYQPFKGQIA
GRVNGVLLSNGSGEAVAYAMFNLEDRGPMIIEPGEKVYAGMIIGIHTRDNDLEVNVLKGK
QLTNIRAAGKDEAVKLTPPIRMTLDRALSWIQEDELMEVTPKSIRLRKMFLDANDRKRFE
KAKLAI