Protein Info for Atu2600 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein (maltose/maltodextrin)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 370 PF00005: ABC_tran" amino acids 20 to 161 (142 residues), 120.3 bits, see alignment E=1.5e-38 PF17912: OB_MalK" amino acids 235 to 286 (52 residues), 42.4 bits, see alignment 1.7e-14

Best Hits

Swiss-Prot: 56% identical to MALK_PHOPR: Maltose/maltodextrin import ATP-binding protein MalK (malK) from Photobacterium profundum (strain SS9)

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 100% identity to atu:Atu2600)

Predicted SEED Role

"Maltose/maltodextrin transport ATP-binding protein MalK (EC 3.6.3.19)" in subsystem Maltose and Maltodextrin Utilization (EC 3.6.3.19)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.19

Use Curated BLAST to search for 3.6.3.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CHL5 at UniProt or InterPro

Protein Sequence (370 amino acids)

>Atu2600 ABC transporter, nucleotide binding/ATPase protein (maltose/maltodextrin) (Agrobacterium fabrum C58)
MGQLYLNNVRKNYGHFEVIKGVQLDIRDGEFVVFVGPSGCGKSTLLRMIAGLEEISAGDV
VINGVKVNELPPVKRGIAMVFQSYALYPHMTVFENIAFPLRVEKMAEEKIKQKVEGVAKI
LQLDQRLQQRPGNLSGGQRQRVAIGRAIVREPKIFLFDEPLSNLDAALRADMRIELTNLH
KTLKATMIYVTHDQVEAMTMADRIVVLNAGEIAQVGAPLELYHKPANLFVAGFIGNPKMN
FLKVTCKSVSAEGVTVAYEGQTITVPVEPRAGLEGKQLTLGIRPEHTGLEAADLNIKVAP
SVIERLGVNTIAYGVAPTGENYCALLPGSAPVVVDEPIVTGIKASDCHLFDESGIALDRR
VDLSVLKLIQ