Protein Info for Atu2525 in Agrobacterium fabrum C58

Annotation: MFS permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 39 to 61 (23 residues), see Phobius details amino acids 77 to 96 (20 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 195 to 215 (21 residues), see Phobius details amino acids 267 to 287 (21 residues), see Phobius details amino acids 299 to 318 (20 residues), see Phobius details amino acids 330 to 348 (19 residues), see Phobius details amino acids 354 to 376 (23 residues), see Phobius details amino acids 388 to 409 (22 residues), see Phobius details amino acids 421 to 441 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 46 to 439 (394 residues), 102.1 bits, see alignment E=5.2e-33 PF07690: MFS_1" amino acids 46 to 325 (280 residues), 126.5 bits, see alignment E=1.8e-40 amino acids 310 to 439 (130 residues), 47.4 bits, see alignment E=2.1e-16 PF06779: MFS_4" amino acids 58 to 219 (162 residues), 41.9 bits, see alignment E=1.3e-14

Best Hits

KEGG orthology group: K05548, MFS transporter, AAHS family, benzoate transport protein (inferred from 100% identity to atu:Atu2525)

Predicted SEED Role

"benzoate MFS transporter BenK" in subsystem Benzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CWU9 at UniProt or InterPro

Protein Sequence (449 amino acids)

>Atu2525 MFS permease (Agrobacterium fabrum C58)
MQGRGDADPYRMARSCVKGRNMSTNYLSAASVRTKNPAGVIATCGLMIMFDGYDLVVYGA
VAPALLKESTWALNPAMVGRAAALTLVGMLLGALFAGTMADRIGRRKVVLLSLAGFSAMM
IASAMTPNFLAFEITRFFAGLGLGALLPTVTALVLEFSPPQRRAQANSLSFLGYLIGGII
SGILGMLLLESYGWRPLMLIGGLPLILLPIFMRFLPESPEWLASKGRQAEADGICDSYGL
QRIVPHAKMQKGGVGALFSEGRLASTLNAWGIHFCSLLLTFGMVNWLPTIMNKMGYDISS
ALSFSVMLNVGAAIGILIGGRFADKGNVKVVVAILFAVGAASIFALTANKGPLLYVFVAL
AGAGTIGTQILANVLVGRLYPVHIRGTGLGFSLAVGRLGGIAGPMIGGLVLQRGLAPEWN
FYIFGSVAVVGLMLTVLTLLYRTSGDARV