Protein Info for Atu2477 in Agrobacterium fabrum C58

Annotation: DNA oxidation protective protein, not DNA-binding

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 162 PF00210: Ferritin" amino acids 21 to 159 (139 residues), 106.1 bits, see alignment E=7.4e-35

Best Hits

Swiss-Prot: 100% identical to DPS_AGRFC: DNA protection during starvation protein (dps) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K04047, starvation-inducible DNA-binding protein (inferred from 100% identity to atu:Atu2477)

Predicted SEED Role

"Non-specific DNA-binding protein Dps / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)" in subsystem Oxidative stress (EC 1.16.3.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.16.3.1

Use Curated BLAST to search for 1.16.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UCK6 at UniProt or InterPro

Protein Sequence (162 amino acids)

>Atu2477 DNA oxidation protective protein, not DNA-binding (Agrobacterium fabrum C58)
MKTHKTKNDLPSNAKSTVIGILNESLASVIDLALVTKQAHWNLKGPQFIAVHELLDTFRT
QLDNHGDTIAERVVQLGGTALGSLQAVSSTTKLKAYPTDIYKIHDHLDALIERYGEVANM
IRKAIDDSDEAGDPTTADIFTAASRDLDKSLWFLEAHVQEKS