Protein Info for Atu2473 in Agrobacterium fabrum C58

Annotation: ABC transporter, substrate binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01497: Peripla_BP_2" amino acids 54 to 284 (231 residues), 97.1 bits, see alignment E=5.8e-32

Best Hits

Swiss-Prot: 34% identical to YCLQ_BACSU: Petrobactin-binding protein YclQ (yclQ) from Bacillus subtilis (strain 168)

KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 100% identity to atu:Atu2473)

Predicted SEED Role

"Iron compound ABC uptake transporter substrate-binding protein" in subsystem Heme, hemin uptake and utilization systems in GramPositives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CHS7 at UniProt or InterPro

Protein Sequence (312 amino acids)

>Atu2473 ABC transporter, substrate binding protein (Agrobacterium fabrum C58)
MAINFTFPVRLLAAAAFSLGAMTASAEEMTIRHAQGETVLKAAPKKVLVLDIPSLDNLDA
LGVEPAGVVGSNLPAYLQKYADGKYLKVGTLFEPDYEAINAAEADLVIVGGRSRAKYPDV
SKITPAVDMSIDSKEFIASVKGNITKLGDIFGKQEEAKKLDVAIDEKVARLKEIAPNSGT
AMILLTNAGKVGVYGPSSRTGWLHTEIGFKPVAADIDDRFDRGDVVSFEYLAEVNPEWLF
VIDRDAGIGRATDPGKAAAQVLDNELVHQTNAWKKKQIVYLDPQAAYIVSSGYTALTTLL
DQVYKAVSEKKS