Protein Info for Atu2366 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF00005: ABC_tran" amino acids 24 to 183 (160 residues), 117.6 bits, see alignment E=6.7e-38 PF13304: AAA_21" amino acids 155 to 213 (59 residues), 28.5 bits, see alignment E=1.6e-10

Best Hits

Swiss-Prot: 66% identical to AOTP_PSEAE: Arginine/ornithine transport ATP-binding protein AotP (aotP) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K10021, octopine/nopaline transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 100% identity to atu:Atu2366)

Predicted SEED Role

"Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CHX8 at UniProt or InterPro

Protein Sequence (258 amino acids)

>Atu2366 ABC transporter, nucleotide binding/ATPase protein (Agrobacterium fabrum C58)
MTDKGACALEADDIHKSFGTHEVLKGVSLKAHKGDVISIIGSSGSGKSTFLRCINFLETP
DRGRVIVNGEEIATKMGRDGKAVPKSWRQVEKLRTGLGMVFQNFNLWAHRTVLENVIEAP
VHVLGVRRHEAVEKAEALLNKVGLYDKKNAYPAFLSGGQQQRAAIARALCMEPAVMLFDE
PTSALDPELVGEVLKVIRDLAEEGRTMLLVTHEMRFARDVSTEVMFLHQGRVEETGPPAQ
VFGNPLSARCREFTGALA