Protein Info for Atu2354 in Agrobacterium fabrum C58

Annotation: transcriptional regulator, MarR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 168 PF12802: MarR_2" amino acids 61 to 118 (58 residues), 53 bits, see alignment E=4.5e-18 PF01047: MarR" amino acids 64 to 119 (56 residues), 44.3 bits, see alignment E=2e-15 PF13463: HTH_27" amino acids 65 to 128 (64 residues), 30.1 bits, see alignment E=7.4e-11

Best Hits

Swiss-Prot: 34% identical to HCRR_THAAR: Putative transcriptional regulatory protein for hcr operon from Thauera aromatica

KEGG orthology group: None (inferred from 100% identity to atu:Atu2354)

Predicted SEED Role

"regulatory protein, MarR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CHY6 at UniProt or InterPro

Protein Sequence (168 amino acids)

>Atu2354 transcriptional regulator, MarR family (Agrobacterium fabrum C58)
MALRLAHSNGPRTEKSESGSAEAAHNTAIDYGLLTTAISYHLRHSQLAVANGFADVLAEQ
GLRPADFSVLVIVGGNPGLKQSDVAEALGIQRANFVAIVDSMEEKGLLVRRKSEEDRRVH
FLDMTEEGSSLLDRLSNTWRDREEKLIDRIGGKKARDQLLALLGRLRD