Protein Info for Atu2332 in Agrobacterium fabrum C58

Annotation: two component sensor kinase/response regulator hybrid

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1231 PF13188: PAS_8" amino acids 148 to 177 (30 residues), 16.2 bits, see alignment (E = 3.6e-06) amino acids 279 to 336 (58 residues), 27.5 bits, see alignment 1e-09 amino acids 409 to 445 (37 residues), 21 bits, see alignment (E = 1.1e-07) PF12860: PAS_7" amino acids 151 to 266 (116 residues), 45 bits, see alignment E=5e-15 amino acids 555 to 665 (111 residues), 44.3 bits, see alignment E=8.5e-15 TIGR00229: PAS domain S-box protein" amino acids 278 to 396 (119 residues), 30 bits, see alignment E=2.4e-11 PF00989: PAS" amino acids 279 to 383 (105 residues), 31.1 bits, see alignment E=9.2e-11 PF08448: PAS_4" amino acids 283 to 385 (103 residues), 41.1 bits, see alignment E=8.5e-14 PF13426: PAS_9" amino acids 287 to 387 (101 residues), 28.6 bits, see alignment E=6.6e-10 amino acids 558 to 660 (103 residues), 10.9 bits, see alignment E=0.00021 PF00512: HisKA" amino acids 681 to 746 (66 residues), 77.6 bits, see alignment 2.7e-25 PF02518: HATPase_c" amino acids 793 to 908 (116 residues), 88.2 bits, see alignment E=2.3e-28 PF00072: Response_reg" amino acids 928 to 1042 (115 residues), 56.5 bits, see alignment E=1.3e-18 amino acids 1100 to 1215 (116 residues), 89.4 bits, see alignment E=7.8e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu2332)

Predicted SEED Role

"FIG00984032: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CXB2 at UniProt or InterPro

Protein Sequence (1231 amino acids)

>Atu2332 two component sensor kinase/response regulator hybrid (Agrobacterium fabrum C58)
MDCRGVEYRLTEGCGLLEKACRAVAALELPACIKDGELRYVVVNEAYGRVMGRAPSAFEG
QTSLSLSGDIRDAEREDRERRSLVFATDEAIACHAALSAQSHMLRCERFIGDDGSLFLFE
VFEEMPSAVSRKSAAVGGASDILFSSGVMDFIDAGIVVYDRDNQLVYCNARFAEFYSDLD
IELKPGIRLEALMKTLYSSSVYRCAKNDGPSFEDWMQKQLHDFSLPYLERVEQFADGRWV
RMVNKRLENGMLVGLRVDVTEFKAHETLLSTQIRETWLLRAALEQLPVGVFLRDQDRRLT
YANAAYNTFLGGNLADHIGKTETEMFPQNGPRFRQENERILQTGEAIERTGNMPWRDGGA
VPVITRLGRVATPDDEYYLVGSVTDVSLLQDREKALIAAQAEAEALHRQLQAVLRALPVG
VLLLNADLVIEYVNPFFYQVWGEIGGEKSLVGKSYREFMEMNFDSGLYDYGDRPFDDVYE
ERVQRLLKADAFAPREVRSKSGKVTVISKTRLEGGKILSTYADVTDVRMRDAEISKARAE
LERVGEYMQGATRAMAQGLVLVEQGTIIMSNEAMARMFDVPPHLLEKGRNWAGFFAHCAG
RGDFGTAAEAGETLRIWRENIAANRPFSWLVHVAGKSWLNLEATNSSGNYWLIIVTDVTE
MKVREEELQRLLSRAEAADRAKSEFLANMSHEIRTPMNGVLGMAELLAKSKLDTRQKTFT
DIIVKSGNALLTIINDILDFSKIEAGQMKLRSVPFDPAEAVEDVVSLLSSAALEKDIELI
VRIDASVSGKVIGDAGRFRQIVTNIVGNAVKFTETGHVLVELSAQSAEASESIFSLRVED
SGIGIPVDKLETIFDKFSQVDGSATRRHEGTGLGLAITVGLVGLFDGKINVVSEVGRGSA
FEVDIPFQVMERRRDVPLLSVAIDDIRVLVIDDNDVNRRILTEQLRSWGIDGHAVENGPS
GIAVLQEAASLGFAIDAIILDYHMPVMNGLDVVERIRADKRFDDIAIVFLTSMDVVGDET
LFTDLSVQAHLMKPARARLLRSTLFDVVRDVRLKRIRQHPLAQGTGGEKARPESRPAEKK
QRAEAPATVPERSRPCLLDVLVAEDNDVNQIVFSQILQQAGLRFLIVGNGKRAVQAWEEY
NPALILMDVSMPVMNGHQATQAIRAAEQAAGDSRHVPVIGVTAHTQEADRERCLEAGMDD
YLSKPISPESLEDKIAQWLGENVLRRDAPGV