Protein Info for Atu2180 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 TIGR03915: probable DNA metabolism protein" amino acids 9 to 242 (234 residues), 214.6 bits, see alignment E=2.7e-67 PF13566: DUF4130" amino acids 81 to 241 (161 residues), 132.5 bits, see alignment E=1.3e-42 TIGR03914: uracil-DNA glycosylase family domain" amino acids 244 to 478 (235 residues), 347.6 bits, see alignment E=5e-108 TIGR00758: uracil-DNA glycosylase, family 4" amino acids 302 to 464 (163 residues), 130.9 bits, see alignment E=5.8e-42 PF03167: UDG" amino acids 316 to 460 (145 residues), 115.6 bits, see alignment E=2e-37

Best Hits

KEGG orthology group: K02334, DNA polymerase bacteriophage-type [EC: 2.7.7.7] (inferred from 100% identity to atu:Atu2180)

Predicted SEED Role

"Domain often clustered or fused with uracil-DNA glycosylase / Uracil-DNA glycosylase, putative family 6"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CI76 at UniProt or InterPro

Protein Sequence (481 amino acids)

>Atu2180 hypothetical protein (Agrobacterium fabrum C58)
MYGPVLEGRGEFGEWRDAARAALAADIRPEMIDWRLRDDGAGLLDFAGEPLPVVAAGDGQ
VSVPASFVALAQAIICHSEPGRFALLYRLLWRLKRDRALLQFKSDPDVAEARLLEKSVRR
DCHKMTAFVRFKEVPLPQGQGGRRRFIAWFEPDHFIVERTAAFFQRRFTDMDWLIATPKG
SARWDGDELQTSREAAVKPDLTDETDELWRTYYANIFNPARLKIKAMTAEMPKKYWKNLP
EADLIPGLVLGAEARVLEMAAKAASQPQPFHHRLQAAASAREMPQPVSDGTLQSLAREAR
QCTRCALHCKATQTVFGEGPEDADIMIVGEQPGDNEDLAGKPFIGPAGQLFDRTLREIGA
ERKKLYVTNAVKHFKYETRGKRRIHQRPNAGEVEQCRWWLNREIALVRPKLIVAMGATAL
YALTGGKEKVSEIRGRPLPMEEGRTLFVTVHPSYLLRLADIRAKEAEMARFRMDMEIIRK
F