Protein Info for Atu2179 in Agrobacterium fabrum C58

Annotation: GGDEF family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 379 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 39 to 58 (20 residues), see Phobius details amino acids 67 to 87 (21 residues), see Phobius details amino acids 100 to 120 (21 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 185 to 209 (25 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 220 to 374 (155 residues), 152.7 bits, see alignment E=3.8e-49 PF00990: GGDEF" amino acids 221 to 371 (151 residues), 142 bits, see alignment E=7.3e-46

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu2179)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CXP3 at UniProt or InterPro

Protein Sequence (379 amino acids)

>Atu2179 GGDEF family protein (Agrobacterium fabrum C58)
MLGELDLATVILMQKCSYIVGLLSFIYLKMSNRGLPGPVHLAAGFAAMTVGSTLAGYGEW
KILSPALWELGSVLFGIAGYALIWLGLKTLSDGRFVNRKTILFTCLVALLAIGVALQVAG
NNTFRAALFNGCAALAYLGGAGVLFARWRKEPLLSRLALGAITGVSGLISLAVMKSVLFP
GYASINLVTAFFFIIMLNFAISLFVMMLVAERSERKLLVLANTDPLTGVKNRRFFFQTMP
AAPDPADAAMLLDIDHFKSINDRFGHAVGDSVLQEVARRISGSIRGGDVLARYGGEEFII
FLPGAGVDKACMIGERIRDAVAINEVDCGGLRVGVTISIGVATTGDMRCDLQMLAEKADR
ALYRAKTEGRNCVREALAA