Protein Info for Atu2157 in Agrobacterium fabrum C58

Annotation: tyrosine/serine protein phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 186 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13350: Y_phosphatase3" amino acids 33 to 146 (114 residues), 36.4 bits, see alignment E=8.8e-13 PF03162: Y_phosphatase2" amino acids 34 to 135 (102 residues), 37.8 bits, see alignment E=2.3e-13 PF04273: BLH_phosphatase" amino acids 43 to 131 (89 residues), 33.2 bits, see alignment E=7.6e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu2157)

Predicted SEED Role

"FIG00364730: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CI85 at UniProt or InterPro

Protein Sequence (186 amino acids)

>Atu2157 tyrosine/serine protein phosphatase (Agrobacterium fabrum C58)
MYSVLKFLKITAIGLVALPVLAGAHMGIGQLTGNFHEVIPGELYRSAQPSGKDIAAYAKA
YGIKTIINLRDEKREGWYEAESLAAKNNGIRLVDYPLSSSEKVSVEDSETLAAVLRNAEK
PVLIHCEHGANRTGLASAIYVAVVAGKSEAAAEFQLSPYYGHVPIPGIGRYEMYQSWDDF
EETIGF