Protein Info for Atu2150 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 PF00005: ABC_tran" amino acids 20 to 161 (142 residues), 130.1 bits, see alignment E=1.3e-41 PF13304: AAA_21" amino acids 118 to 195 (78 residues), 32.4 bits, see alignment E=1.5e-11 PF08402: TOBE_2" amino acids 275 to 349 (75 residues), 43.3 bits, see alignment E=4.8e-15

Best Hits

Swiss-Prot: 44% identical to MALK_VIBVU: Maltose/maltodextrin import ATP-binding protein MalK (malK) from Vibrio vulnificus (strain CMCP6)

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 100% identity to atu:Atu2150)

Predicted SEED Role

"Ferric iron ABC transporter, ATP-binding protein" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CI89 at UniProt or InterPro

Protein Sequence (352 amino acids)

>Atu2150 ABC transporter, nucleotide binding/ATPase protein (Agrobacterium fabrum C58)
MSFLTLSNIKKSFGSVQVVHDFNMAIEKGEFVSFLGPSGCGKTTVLRMIAGFEIPTGGSI
VINGKDQTTLRPNQRNIGMVFQAYALFPNMNVYENVAFGLKVAGKPKAEIDARVKEMLQL
IHLEHLADRYPYQMSGGQQQRVALARALAPKPEVLLLDEPLSALDAKIRVSLREEIRQIQ
QKLGITTIFVTHDQEEALSISDRIVVMNGGRADQIGSPFDIYNKPATRFVASFVGTLNLI
DATVVDSSSNTIRVGEQQITLPKPVDAANGEKITLALRPEAGSLGSDAKGDVAISGLVTS
SQFLGSVIRTRLDLGGSTLSFDMFNDPGTAPPAVGERVTLKFAAGDLMLIKD