Protein Info for Atu2090 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein (sugar)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 39 to 58 (20 residues), see Phobius details amino acids 65 to 87 (23 residues), see Phobius details amino acids 99 to 118 (20 residues), see Phobius details amino acids 126 to 152 (27 residues), see Phobius details amino acids 165 to 188 (24 residues), see Phobius details amino acids 199 to 220 (22 residues), see Phobius details amino acids 253 to 275 (23 residues), see Phobius details amino acids 289 to 307 (19 residues), see Phobius details amino acids 319 to 338 (20 residues), see Phobius details amino acids 344 to 369 (26 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details amino acids 410 to 429 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 27 to 236 (210 residues), 79.6 bits, see alignment E=2.5e-26 amino acids 235 to 427 (193 residues), 25.6 bits, see alignment E=5.9e-10 PF07690: MFS_1" amino acids 33 to 371 (339 residues), 80.2 bits, see alignment E=1.5e-26 amino acids 296 to 430 (135 residues), 37 bits, see alignment E=2e-13 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 33 to 423 (391 residues), 447.8 bits, see alignment E=1.8e-138

Best Hits

Swiss-Prot: 55% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to atu:Atu2090)

Predicted SEED Role

"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CIA9 at UniProt or InterPro

Protein Sequence (434 amino acids)

>Atu2090 ABC transporter, membrane spanning protein (sugar) (Agrobacterium fabrum C58)
MTDAVSRVSSTAGNSNAVKTNSPARVLTASLVGTTIEFFDFYVYATAAVLVFPALFFPNS
DPTTALLASFATFSIAFFARPLGAVVFGHYGDRVGRKATLVAALLTMGVSTVVIGLLPTY
ETAGVLAPLLLALCRFGQGFGLGGEWGGAVLLATENAPPGKRSWYGMFPQLGAPVGLFLS
SGVFWILLHFMSQEALLSWGWRIPFVASIILIAVGMWVRLSITETPDFQKAIEKEERVAV
PIAELFRSHKRSLVLGTFVALATFVLFYIGTAYLLSYNVKVLKIPFLDALEVQILGSIVF
GIFIPVAGKLAEKFGRREVLIVTTILIGLFSFLLPSLMTGGEGSIFVFAALAMMLMGMTY
GLIGTALAAPFPTRVRYTGSSITFNMAGIFGASLAPYIATWLQVNYGMGYVGYYLCISAL
ITLACIFLSRKDEV