Protein Info for Atu2044 in Agrobacterium fabrum C58

Annotation: HFLC protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01145: Band_7" amino acids 25 to 203 (179 residues), 91.9 bits, see alignment E=2.5e-30

Best Hits

KEGG orthology group: K04087, membrane protease subunit HflC [EC: 3.4.-.-] (inferred from 100% identity to atu:Atu2044)

Predicted SEED Role

"HflC protein" in subsystem Hfl operon

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.-.-

Use Curated BLAST to search for 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CIC9 at UniProt or InterPro

Protein Sequence (307 amino acids)

>Atu2044 HFLC protein (Agrobacterium fabrum C58)
MGNRLTAVLVGLAVLLFLGYSSIFVVNERQQAIVVRFGQIQDVKTAPGLYFKLPFAFMDA
DRVQYVENRALRFDHDNIRVQVSGGKFYEVDAFVVYRITDARRFRQTVSGDQMSAESRLR
TRLDASLRRVYGLRGFESALSDARASMMQEVRDDLRPDAESLGISIVDVRIRRTDLTQEV
SQQTFERMKSERLAEAELIRARGNEAAQRRRAVADREVVELESTAQRQSEVLRGEGDAER
NKVFGVAFQRDPDFFEFYRSMSAYANALNGNGTTLVLSPDSTFFRYFNNINGAPPAAPAA
PAPAPAN