Protein Info for Atu1927 in Agrobacterium fabrum C58

Annotation: Preprotein translocase SECY subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 27 to 45 (19 residues), see Phobius details amino acids 79 to 103 (25 residues), see Phobius details amino acids 123 to 143 (21 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 187 to 205 (19 residues), see Phobius details amino acids 219 to 238 (20 residues), see Phobius details amino acids 274 to 296 (23 residues), see Phobius details amino acids 317 to 339 (23 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details amino acids 398 to 419 (22 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 24 to 430 (407 residues), 430 bits, see alignment E=4.6e-133 PF00344: SecY" amino acids 81 to 418 (338 residues), 382.1 bits, see alignment E=1.1e-118

Best Hits

Swiss-Prot: 55% identical to SECY_VIBCH: Protein translocase subunit SecY (secY) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 100% identity to atu:Atu1927)

MetaCyc: 55% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CY83 at UniProt or InterPro

Protein Sequence (446 amino acids)

>Atu1927 Preprotein translocase SECY subunit (Agrobacterium fabrum C58)
MASAAEQLASNLNFSTFAKAEDLKKRLWFTLAALLVYRLGTHIPLPGLNPEAYAQAFRGQ
ANGILGLFNMFAGGAVERMAIFALGIMPYISASIIVQLMTSVVPSLEALKKEGEAGRKII
NQYTRYGTVLLGTLQAYGIAVGLESGNGLVVDPGMFFRVSTVITLLGGTMFLMWLGEQIT
SRGIGNGISLIIFAGIAAGLPKALAGTLELGRTGALSTPLILMVVIVAIGVIALIVFVER
AQRRLLIQYPKRQVGNRMFQGDTSHLPLKLNTAGVIPAIFASSLLLLPATAAGFAGNTNL
PTWATSIIASLQHGQPLFMALYGLLIAFFAFFYTAIVFNPKDTADNLKKHGGFIPGIRPG
ERTAEYIDYVLTRITVVGAIYLVFVCILPETLIARTGIPLALGGTSLLIVVSVTLDTVAQ
IQGHLIAQQYEGLIKKSKLRGGKRGR