Protein Info for Atu1915 in Agrobacterium fabrum C58

Annotation: htrA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR02037: peptidase Do" amino acids 41 to 465 (425 residues), 503.9 bits, see alignment E=2e-155 PF00089: Trypsin" amino acids 91 to 250 (160 residues), 68.3 bits, see alignment E=2.2e-22 PF13365: Trypsin_2" amino acids 94 to 229 (136 residues), 116.4 bits, see alignment E=4.7e-37 PF13180: PDZ_2" amino acids 269 to 360 (92 residues), 40.2 bits, see alignment E=8.6e-14 amino acids 397 to 445 (49 residues), 31.3 bits, see alignment 5e-11 PF17820: PDZ_6" amino acids 296 to 347 (52 residues), 35.6 bits, see alignment 1.6e-12 amino acids 406 to 446 (41 residues), 33.3 bits, see alignment 8e-12 PF00595: PDZ" amino acids 397 to 442 (46 residues), 27.3 bits, see alignment 9.8e-10

Best Hits

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 100% identity to atu:Atu1915)

Predicted SEED Role

"macromolecule metabolism; macromolecule degradation; degradation of proteins, peptides, glycopeptides"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CY88 at UniProt or InterPro

Protein Sequence (468 amino acids)

>Atu1915 htrA family protein (Agrobacterium fabrum C58)
MRGVLKYLSTGFLAALVLLPVGARAQDNKTVPASHTEMQLSFAPLVKRTAGAVVNVYAER
VVQRRVSPFAGDPFFEQFFGQQMPNRTEKQSSLGSGVIVTAGGLVVTNNHVIDGADDIKV
ALADGREFSSKVLMKDDRVDLAVLQIDAKEQFPVLSLGDSDKIEVGDLVLAIGNPFGVGQ
TVTSGIVSGLARNQVTQGDFGFFIQTDASINPGNSGGALMNMAGELVGINTAIFSKGGGS
NGIGFAIPANLVRVFVAAAERGDANFQRPYIGATFDPVTSDVAEALGLHRARGALVVGVT
KGGPAEKAGIEPGQVVTAVNGLEVEHPDALGYRLTTAGIGKSAELTVVEKGKEKKLTIAL
NTAPETAPRDERLLEGRNPFAGATVANLSPKLADELRMPSQVTGVVITDVKRGSPAYRVG
FQPKDVILSLNGADIGSTAAVEKALDDNPGFWRVEILRDGQRIRQFLR