Protein Info for Atu1903 in Agrobacterium fabrum C58

Annotation: glycerol kinase 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00370: FGGY_N
  • amino acids 4 to 243 (240 residues), 205.9 bits, E=7.7e-65
• PF02782: FGGY_C
  • amino acids 253 to 438 (186 residues), 114.9 bits, E=4.4e-37

Best Hits

Swiss-Prot: 46% identical to APLK_PECAS: Apulose kinase (aplK) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K00864, glycerol kinase [EC: 2.7.1.30] (inferred from 100% identity to atu:Atu1903)

MetaCyc: 46% identical to apulose kinase (Pectobacterium atrosepticum SCRI1043)
RXN-20928 [EC: 2.7.1.233]

Predicted SEED Role

"Unknown pentose kinase TM0952"

MetaCyc Pathways

• glycerol and glycerophosphodiester degradation (3/4 steps found)
• D-apiose degradation I (2/3 steps found)
• glycerol degradation I (2/3 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.30

Use Curated BLAST to search for 2.7.1.233 or 2.7.1.30

Sequence Analysis Tools

See A9CIG9 at UniProt or InterPro

Protein Sequence (489 amino acids)

>Atu1903 glycerol kinase 2 (Agrobacterium fabrum C58)
MRAILSIDQGTTNSKAILVSESGELLARGSSPVGITYPQPGWVEQDPNRIWASVREAISA
CLAAAPSDVSVEAIAISNQRESVTIWDGETGEPLGPVLSWQCRRTAQDCADLIAKGQSER
VMALTGLPIDPMFPGAKMRWLLERAPKGRKLRLGTIDSWLIHCFTGGKVHACDASNAARS
QVLDLNRQVWSDELCDLFGIDINALPDLRDSSGDFGVTSGVPGIKDGTPILAAIGDSHAA
LFGHGAFNPGDGKVTFGTGSSVMTTLPHFIAPERGITTTVAWRLGGKPTFAFEGNILVSA
ASLPWMTDILGLPDVAALVELAATAEPEGPGFVPAFVGLGAPYWDTNARALFSQINFSTT
RAQMARAVTDSIAFQVHDVFAAMRAQSPSGFGRLFVDGGPSQNRFLMQCVADMLEHPVIQ
RDAPEASALGAAYLAGLALGVWSDLNAIAALNSNGNTIATSTGESRQRLGIWRDAIARST
LPVTSGNGE