Protein Info for Atu1728 in Agrobacterium fabrum C58

Annotation: TrpR binding protein WrbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 TIGR01755: NAD(P)H:quinone oxidoreductase, type IV" amino acids 2 to 197 (196 residues), 361.6 bits, see alignment E=6e-113 PF03358: FMN_red" amino acids 3 to 142 (140 residues), 39.6 bits, see alignment E=6.2e-14 PF00258: Flavodoxin_1" amino acids 6 to 124 (119 residues), 38.4 bits, see alignment E=2.1e-13

Best Hits

Swiss-Prot: 100% identical to NQOR_AGRFC: NAD(P)H dehydrogenase (quinone) (Atu1728) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K03809, Trp repressor binding protein (inferred from 100% identity to atu:Atu1728)

MetaCyc: 59% identical to NAD(P)H:quinone oxidoreductase (Escherichia coli K-12 substr. MG1655)
NAD(P)H dehydrogenase (quinone). [EC: 1.6.5.2]

Predicted SEED Role

"Flavoprotein WrbA"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.5.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P58795 at UniProt or InterPro

Protein Sequence (199 amino acids)

>Atu1728 TrpR binding protein WrbA (Agrobacterium fabrum C58)
MTKVLVLYYSSYGHIETMAYAVAEGVESTGAEAVVKRVPELVPEEVAKSSHFKMDQPAPV
ATVDELAEYDAIIVGAGTRFGTVASQMRNFWDQTGGLWFSGKLVGKVGSAFTSSATQHGG
QESTILGFIPTFLHHGMAVVGLPYAFQGQMGVDEIKGGSPYGASTITDGDGSRQPSAIEL
DAARYQGAHVAKLAAKLSA