Protein Info for Atu1719 in Agrobacterium fabrum C58

Annotation: valyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 947 transmembrane" amino acids 537 to 554 (18 residues), see Phobius details TIGR00422: valine--tRNA ligase" amino acids 3 to 925 (923 residues), 1059.2 bits, see alignment E=0 PF00133: tRNA-synt_1" amino acids 15 to 631 (617 residues), 504.7 bits, see alignment E=4.7e-155 PF09334: tRNA-synt_1g" amino acids 44 to 94 (51 residues), 27.8 bits, see alignment 2.8e-10 amino acids 570 to 634 (65 residues), 30.4 bits, see alignment 4.6e-11 PF13603: tRNA-synt_1_2" amino acids 261 to 322 (62 residues), 26.4 bits, see alignment 1.2e-09 PF08264: Anticodon_1" amino acids 673 to 821 (149 residues), 144 bits, see alignment E=8.5e-46 PF10458: Val_tRNA-synt_C" amino acids 879 to 942 (64 residues), 61.9 bits, see alignment 1.5e-20

Best Hits

Swiss-Prot: 100% identical to SYV_AGRFC: Valine--tRNA ligase (valS) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K01873, valyl-tRNA synthetase [EC: 6.1.1.9] (inferred from 100% identity to atu:Atu1719)

Predicted SEED Role

"Valyl-tRNA synthetase (EC 6.1.1.9)" (EC 6.1.1.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UEN6 at UniProt or InterPro

Protein Sequence (947 amino acids)

>Atu1719 valyl-tRNA synthetase (Agrobacterium fabrum C58)
MLEKTYDSASVEPKIAKAWDEANAFRAGANAKPGAETFTIVIPPPNVTGSLHMGHALNNT
LQDILVRFERMRGKDVLWQPGMDHAGIATQMVVERKLMENQLPGRREMGREAFVEKVWEW
KAESGGLIFNQLKRLGASCDWSRERFTMDEGLSEAVLEVFVTLYKQNLIYKAKRLVNWDP
KLQTAISDMEVEQIEVKGNLWHFRYPLEKGVTYEYPVAFDADGTPTEFETRDYIVVATTR
PETMLGDTGVAVNPEDERYKGIVGKHVILPIVGRKIPIVADDYADPTAGTGAVKITPAHD
FNDFEVGKRCGLRAINVMNIDGTISIKENEDFLEGLSHPAALHGAWDRLEGQDRFTARKI
IVEIFEEAGLLDKIEPHKHVVPHGDRGGVPIEPRLTDQWWVDNKTLAQPAIASVREGRTN
FVPKNWENTYFQWMENIQPWCISRQLWWGHQIPAWYGPDGQVFVEKTEEEALQAAIQHYI
AHEGPWKAWVEEKLENFAPGEILTRDEDVLDTWFSSALWPFSTLGWPEQTPELARYYPTN
VLVTGFDIIPFWVVRMMQMGLHFMKDDAGNPVEPFSTVYIHALVRDKNGQKMSKSKGNVI
DPLELIDEYGADALRFTLAIMAAQGRDVKLDPARIAGYRNFGTKLWNATRFAEMNGVKRD
PHFLAETASLTINRWILTELANTARDVTAALENFRFNDASGILYRFVWNQFCDWYLELLK
PVFSGEDEEAKRESQACAAYVLEEIYKLLHPFMPFMTEELWAHTAGEGEERDDLLCLTDW
PEPEFRDDAAAAEINWLIDLVSGIRSARAEMNVPPGATASLVVVGANTSTEARLDRHAAA
IRRLARADEIRGGDVAPKGSAQIIVGEATVCLPLGNLVDLAAEQARLEKAIGKVDAEMER
IDKKLSNEKFVANADPEVVAAERERKAELDVQLASLRTALTRVSEAG