Protein Info for Atu1711 in Agrobacterium fabrum C58

Annotation: arginyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 585 PF03485: Arg_tRNA_synt_N" amino acids 9 to 93 (85 residues), 71.4 bits, see alignment E=2e-23 TIGR00456: arginine--tRNA ligase" amino acids 17 to 584 (568 residues), 364.1 bits, see alignment E=5.7e-113 PF00750: tRNA-synt_1d" amino acids 118 to 180 (63 residues), 44.2 bits, see alignment E=3.2e-15 amino acids 313 to 417 (105 residues), 28.9 bits, see alignment E=1.5e-10 PF05746: DALR_1" amino acids 454 to 584 (131 residues), 111.1 bits, see alignment E=8.8e-36

Best Hits

Swiss-Prot: 100% identical to SYR_AGRFC: Arginine--tRNA ligase (argS) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K01887, arginyl-tRNA synthetase [EC: 6.1.1.19] (inferred from 100% identity to atu:Atu1711)

Predicted SEED Role

"Arginyl-tRNA synthetase (EC 6.1.1.19)" (EC 6.1.1.19)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UEP4 at UniProt or InterPro

Protein Sequence (585 amino acids)

>Atu1711 arginyl-tRNA synthetase (Agrobacterium fabrum C58)
MNIFADFDTRIKNALETLDLVKENREKVDFSRITVESPRDLSHGDVATNAAMVLAKPLGT
NPRALAELLVPALQADGDVDGVNVAGPGFINLKVSVGYWQRLLADMIGQGVDFGRSTVGA
GQKINVEYVSANPTGPMHVGHCRGAVVGDTLANLLAFAGYGVTKEYYINDAGSQIDVLAR
SVFLRYREALGEDIGSIPSGLYPGDYLVPVGQALADEYGIKLRAMPEEKWLPIVKDKAID
AMMVMIREDLALLNVRHDVFFSERTLHEGNGGPILSAINDLTFKGHVYKGTLPPPKGELP
DDWEDREQTLFRSTEVGDDMDRALMKSDGSYTYFAADVAYFKNKFDRGFSEMIYVLGADH
GGYVKRLEAVARAVSEGKSKLTVLLCQLVKLFRDGEPVKMSKRSGDFVTLRDVVDEVGRD
PVRFMMLYRKNSEPLDFDFAKVTEQSKDNPVFYVQYAHARCKSIFRQAQEAFPGLAPSAE
DMAASVALISDINELQLVAKLAEYPRLIESAALSHEPHRLAFYLYDLAGSFHGHWNKGKD
HQELRFINDKNRELSIARLGLVNAVANVLKSGLTLLGADAPDEMR