Protein Info for Atu1691 in Agrobacterium fabrum C58

Annotation: GGDEF family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 173 to 336 (164 residues), 147.7 bits, see alignment E=1.3e-47 PF00990: GGDEF" amino acids 176 to 334 (159 residues), 146.3 bits, see alignment E=3.5e-47

Best Hits

KEGG orthology group: K13590, diguanylate cyclase (inferred from 100% identity to atu:Atu1691)

Predicted SEED Role

"diguanylate cyclase (GGDEF domain) with PAS/PAC sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CYR0 at UniProt or InterPro

Protein Sequence (356 amino acids)

>Atu1691 GGDEF family protein (Agrobacterium fabrum C58)
MNTASTPKTTGPDIAGQIAYAMRSMGVSPIPRNYSLFYEAYIGSNPALTKDLAALGNRVT
QEDLDELSSRYGEGNPNRSIDDAQDKLRRELEALLGTLKREQSSIENYNRILGETRQRID
DKNAASNNILRNAISLLADATGSKIIDGEKTFNDVNRHAEEMHQVRLELDEYKRIANTDS
LTRLSNRRAFDDRLASVYDSSIGLQYTTLVLLDIDHFKRINDTFGHPVGDKILATVASVI
RANVRKDGFVARSGGEEFAIILDGNTPEEVMVMCERIRLSLESTPFRNSRSGADYGTVTI
SIGFASAARASNPSELYGHADTALYHAKETGRNRSVFYEDGMQNNYTGKNWLIYRT