Protein Info for Atu1664 in Agrobacterium fabrum C58

Annotation: trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 492 PF05697: Trigger_N" amino acids 1 to 150 (150 residues), 120.8 bits, see alignment E=9.3e-39 TIGR00115: trigger factor" amino acids 11 to 425 (415 residues), 424.9 bits, see alignment E=1.5e-131 PF00254: FKBP_C" amino acids 164 to 245 (82 residues), 68 bits, see alignment E=1.2e-22 PF05698: Trigger_C" amino acids 269 to 425 (157 residues), 150.3 bits, see alignment E=7.6e-48

Best Hits

Swiss-Prot: 100% identical to TIG_AGRFC: Trigger factor (tig) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K03545, trigger factor (inferred from 100% identity to atu:Atu1664)

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UEU0 at UniProt or InterPro

Protein Sequence (492 amino acids)

>Atu1664 trigger factor (Agrobacterium fabrum C58)
MQVIETLADGLKRELKIVIPAADMKARLDERLVDAKDKVRINGFRPGKVPMGHLKKMYGK
SIMADLVNELVREKPSEILSSRGEKSATQPAISMTEDEQEAEKILSAESDFEFTVAYEII
PAIELKANDGIKVTREVVEVSEDEINEQILKIAESARTYETKKGKAADGDRVTMNYLGKV
DGVAFDGGTAEDAELVLGSGRFIPGFEDQLVGVKAGDEKTITVTFPADYPAANLAGKDAT
FDVTVKEVAAAAAVEINDELAEKLGLESAEKLKEIVKGQIESQFGNVTRQKVKRQILDQL
DEMYKFDTPAGLVDAEFDNIWRQINTDLAQSGKTFADEDTTEEEAREEYRKLAERRVRLG
LVLSEIGEKAGVEVTEEEMQRALFQQLQQFPGQQKEILDFFRNTPGASASLRAPIFEEKV
IDKLLTEISVTDKTVSKEELLADDGEEETETKKKAPAKKKAAAKADDAAEGEEAAPKKKA
PAKKKATEADAE